Dengue, a mosquito-borne disease emerged in Nepal in the form of Dengue Fever (DF), Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS). The earliest cases were detected as early as 2005. The sporadic cases continued and outbreaks occurred in 2006 and 2010. Initially most of the reported cases had travel history to neighbouring country (India), however lately indigenous cases were also reported. Studies carried out in close collaboration of WARUN/AFRIMS in the year 2006 by EDCD/NPHL showed all 4 sub-types (DEN-1, DEN-2, DEN-3 and DEN-4) of Dengue virus circulation in Nepal. In 2012, a total of 183 confirmed dengue cases were reported. More than forty percent (n=77) of these cases were from Jhapa district alone, where an outbreak was reported from Mechinagar municipality and Dhulabari VDC. Of these 77 cases in Jhapa, 62% were male, and majority of all infected people were adults. Three severe cases were reported from Jhapa but no deaths were reported.